Isolation and Characterization of Neural Crest Progenitors from Adult Dorsal Root Ganglia
نویسندگان
چکیده
منابع مشابه
Imaging neural crest cell dynamics during formation of dorsal root ganglia and sympathetic ganglia.
The neural crest is a migratory population of cells that produces many diverse structures within the embryo. Trunk neural crest cells give rise to such structures as the dorsal root ganglia (DRG) and sympathetic ganglia (SG), which form in a metameric pattern along the anterior-posterior axis of the embryo. While static analyses have provided invaluable information concerning the development of...
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Chromaffin cells of the adrenal medulla are neural crest-derived cells of the sympathoadrenal lineage. Unlike the closely-related sympathetic neurons, a subpopulation of proliferation-competent cells exists even in the adult. Here, we describe the isolation, expansion, and in vitro characterization of proliferation-competent progenitor cells from the bovine adrenal medulla. Similar to neurosphe...
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To assess the effects of reduced competition for peripheral targets on developing brachial dorsal root ganglia (DRG), chick embryos were subjected to partial ablations of the brachial neural crest at stages 13 or 14 (Hamburger, V., and H.L. Hamilton (1951) J. Morphol. 88: 49-92), using an ophthalmological cauterization unit. In the initial studies reported here, ganglia developing from the rema...
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Adult neurogenesis, or the creation of new neurons in adult organisms, is an exciting recent area of neurological research. The subgranular zone of the adult hippocampus is one area where hippocampal neural progenitors generate new neurons that functionally integrate into existing neuronal circuitry. Given the role that the hippocampus plays in learning and memory consolidation and its vulnerab...
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Although recent reports have described multipotent, self-renewing, neural crest-derived stem cells (NCSCs), the NCSCs in various adult rodent tissues have not been well characterized or compared. Here we identified NCSCs in the bone marrow (BM), dorsal root ganglia, and whisker pad and prospectively isolated them from adult transgenic mice encoding neural crest-specific P0-Cre/Floxed-EGFP and W...
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ژورنال
عنوان ژورنال: Stem Cells
سال: 2007
ISSN: 1066-5099,1549-4918
DOI: 10.1634/stemcells.2007-0080